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Save the atmosphere, shellfish, carbon dioxide, Manipulating genomes: targeted gene disruption, transformation, vectors. Gene editing. CRISPR-Cas9 system, zinc-finger nucleases, ZFNs, transcription activator-like effector nucleases, TALENs, engineered meganucleases. Genome-enabled mycology. Fungi as cell factories. Producing heterologous proteins. Recombinant protein production by filamentous fungi. Ecosystem services. Emerging Infectious Disease, EID. Cutaneous chytridiomycosis, amphibians. Aspergillosis disease of coral. Snake fungal disease. White-nose syndrome of bats. Mycoses, fungus diseases humans. Functional genomics. RNA interference. Transformation, Agrobacterium-mediated transformation, AMT. Site-directed mutagenesis. Engineered nucleases. Introns. Alternative splicing. Transposons. Ploidy and genomic variation. Sequencing fungal genomes. Annotating the genome. Fungal genomes. Integrated pest management programmes. fungicide resistance. 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